When people think of Japanese skincare, Hada Labo is one of the first names that comes up — and for good reason. Since its launch in 2004, this brand has been loved by people of all ages across Japan and around the world, and it shows no signs of slowing down.
But if you’ve ever stood in a Japanese drugstore (or scrolled through iHerb) staring at a wall of Hada Labo bottles wondering which one to pick — I get you. The lineup has grown a lot over the years, and the differences between each series aren’t always obvious.
In this post, I’ll break down every Hada Labo line, explain who each one is for, and share my honest three-year review of the one I reach for every single day. By the end, you’ll know exactly which bottle is right for you.
What is Hada Labo?
Hada Labo (肌ラボ) is a Japanese skincare brand launched in 2004 under Rohto Pharmaceutical — one of Japan’s most trusted pharmaceutical companies. The brand’s philosophy is beautifully simple: “Perfect Simple — only what your skin truly needs.”
Rather than layering in unnecessary additives, Hada Labo strips everything back to the essentials, applying the same quality standards used in pharmaceutical manufacturing to its skincare formulas.
The brand’s signature ingredient is hyaluronic acid — and not just any kind. Rohto has been researching hyaluronic acid in ophthalmology (eye care) for decades, and that deep scientific expertise carries directly into every Hada Labo product. One gram of hyaluronic acid can hold up to six litres of water — and Hada Labo has been developing new, more advanced forms of it since day one.
What Hada Labo Stands For
① Formulation — Nothing unnecessary Fragrance-free, colorant-free, alcohol-free, paraben-free, and oil-free. As a pharmaceutical company, Rohto pursues only what the skin truly needs.
② Efficacy — A deep commitment to hyaluronic acid Drawing on decades of ophthalmic research, Hada Labo continues to develop new forms of HA — each with unique molecular weights and functions to hydrate at different skin depths.
③ Quality — Pharmaceutical-grade manufacturing Purified water, minimised human intervention in the production line, and strict cleaning standards. This is a level of quality control rarely seen in cosmetics.
④ Price — Quality you can use generously Semi-automated manufacturing technology developed for eye drop production, combined with standardised global packaging, keeps costs low — so high quality stays accessible.
⑤ Sustainability — Refill pouches since 2005 Hada Labo introduced eco refill pouches just one year after launch, and has been rolling out biomass containers since 2019. Their environmental commitment has been there from the very beginning.
In short: a genuinely clean, research-backed formula, available at drugstore prices, with sustainability built in from the start. It’s no wonder this brand has become a staple in so many routines.
The Hada Labo Lineup: 6 Series Explained
Hada Labo currently offers six main series (plus premium versions within some lines). Here’s everything you need to know about each one.
① Gokujyun (極潤) — The White One
Best for: Normal to dry skin Who it’s for: Those wanting simple, no-fuss hydration; Hada Labo first-timers; budget-conscious users Key ingredients: Fermented Hyaluronic Acid, Hyaluronic Acid, Super Hyaluronic Acid, Nano Hyaluronic Acid
The original. The classic. Four types of hyaluronic acid work together to hydrate at different depths, building a solid moisture base for your skin. If you’ve never tried Hada Labo before, this is your starting point. There’s also a Light version for oilier skin types.
Formulated at a weakly acidic pH. Fragrance-free, colorant-free, oil-free, alcohol-free, paraben-free.
② Gokujyun Premium (極潤プレミアム) — The Gold One
Best for: Dry skin Who it’s for: Those dealing with serious dryness or a compromised skin barrier; fans of rich, viscous toners Key ingredients: Hyalorепair, 3D Hyaluronic Acid, Skin-Adhering HA, Super HA, Fermented HA, Penetrating HA
Hada Labo’s most hydration-packed formula — featuring 8 types of hyaluronic acid, the most of any product in the lineup. Despite the rich texture, it absorbs beautifully without heaviness. Think of this as the serum-level upgrade from the original Gokujyun.
Fragrance-free, colorant-free, oil-free, alcohol-free, paraben-free.
③ Shirojyun (白潤) — The Light Blue One ⭐ Annie’s Holy Grail
Best for: Normal to oily skin Who it’s for: Those wanting brightening and clarity; anyone dealing with acne or uneven texture; fans of lightweight toners Key ingredients: Tranexamic Acid (brightening), Allantoin (soothing), Vitamin C Phosphate Mg, Vitamin E, Barley Extract, Fermented Barley Extract, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid Na-2
This is the one I reach for every single day — and have for nearly three years. I’ll share my full honest review below, but in short: Shirojyun does it all. It hydrates, works to prevent dark spots, soothes inflammation, and is lightweight enough to use on my face and body without any stickiness. The fact that it’s glycerin-free is a huge bonus for my skin specifically.
There’s also a Moist version for those who prefer a richer feel.
Weakly acidic. Fragrance-free, colorant-free, mineral oil-free, alcohol-free, paraben-free.
④ Shirojyun Premium (白潤プレミアム) — The Blue One
Best for: Normal, dry, and oily skin Who it’s for: Those serious about brightening and moisture; anyone wanting both anti-spot and anti-aging benefits in one step Key ingredients: Tranexamic Acid + Glycyrrhizic Acid 2K, Vitamin C Phosphate Mg, Vitamin E, Hydrolyzed Hyaluronic Acid, Hyaluronic Acid Na-2
Think of this as the upgraded, more intensive version of Shirojyun. It adds Glycyrrhizic Acid 2K (an anti-inflammatory powerhouse) and additional antioxidant vitamins to the formula, making it an especially rich option for anyone wanting to target pigmentation more aggressively while still maintaining hydration.
In Japan, this tends to be the most popular product in the Shirojyun line — and its ingredient profile has drawn comparisons to much pricier luxury toners. A genuinely impressive formula at a fraction of the cost.
Weakly acidic. Fragrance-free, colorant-free, mineral oil-free, alcohol-free, paraben-free.
⑤ Gokujyun Aging Care (極潤エイジングケア) — The Red One
Best for: Normal to dry, mature skin Who it’s for: Those concerned about fine lines, wrinkles, and dark spots; fans of rich, serum-like toners Key ingredients: Niacinamide, Hyaluronic Acid Na, Acetyl Hyaluronic Acid Na, Hydrolyzed Hyaluronic Acid Na
This is Hada Labo’s dedicated anti-aging formula. Niacinamide targets both wrinkles and pigmentation simultaneously — making this a true multi-tasker for more mature skin concerns. Combined with three types of hyaluronic acid, it delivers that serum-in-a-toner experience that makes everyday skincare feel like an upgrade.
Weakly acidic. Fragrance-free, colorant-free, mineral oil-free, alcohol-free, paraben-free.
⑥ Medicated Skin Conditioner (薬用極潤スキンコンディショナー)ーThe Green One
Best for: Normal, oily, and acne-prone skin Who it’s for: Those dealing with breakouts or persistent skin concerns; anyone wanting a lightweight, calming daily toner Key ingredients: Glycyrrhizic Acid + Epsilon-Aminocaproic Acid (medicated actives), Hyaluronic Acid Na-2, Squalane, Barley Extract (Yokuinin), Dokudami Extract, Chamomile Extract
The only medicated (quasi-drug) formula in the lineup, this one is built for calming and rebalancing troubled skin. Three traditional Japanese botanical extracts work alongside medicated actives to reduce inflammation and support clearer skin — while hyaluronic acid keeps hydration in check throughout. It also works beautifully as a morning wipe-down toner.
Worth noting: the ingredient profile has been compared to much pricier luxury toners in Japan. For anyone whose skin responds well to Hada Labo, this could be a very cost-effective find.
Not Sure Where to Start? Here’s My Simple Answer
| Your Skin Goal | Start Here | Why |
|---|---|---|
| First timer / Just want hydration | Gokujyun (White) | The classic. Works for almost every skin type and won’t break the bank. |
| Serious dryness / Barrier repair | Gokujyun Premium (Gold) | 8 types of HA for maximum, lasting moisture. |
| Brightening + daily hydration | Shirojyun (Light blue) ⭐ | Annie’s personal holy grail — hydration AND brightening in one lightweight step. |
| Intensive brightening + anti-aging | Shirojyun Premium(Blue) | Adds anti-inflammatory actives for a more powerful brightening routine. |
| Fine lines / Wrinkles / Dark spots | Aging Care (Red) | Niacinamide + HA — a genuine anti-aging workhorse. |
| Acne / Troubled / Sensitive skin | Medicated Skin Conditioner(Green) | Calming botanicals + medicated actives to rebalance reactive skin. |
You really can’t go wrong with any of them — just pick the one that matches your skin concern and start there. And once you find your match, the refill pouches make it even easier (and more sustainable) to keep going.
Annie’s Honest Review: 3 Years of Shirojyun
I started using Hada Labo Shirojyun about three years ago — and honestly, it’s become one of those products I don’t even think about replacing. It’s just always there.
A bit of background: I noticed that glycerin was causing me to break out and itch, so I made the switch to glycerin-free products. Shirojyun was one of the first I tried — and my skin responded immediately. No irritation, no clogged pores, just calm, hydrated skin.
I use the large bottle (the most economical option) consistently. While I wouldn’t say it’s delivered dramatic brightening results overnight, after nearly three years of daily use, I do notice a genuine difference in my skin tone. When I catch my reflection or stand next to people in photos, my skin looks brighter. And importantly, I haven’t seen new dark spots forming — which I credit partly to this, partly to my sunscreen habits.
In winter, I layer a serum or cream on top because this alone isn’t quite enough for the colder months. But as a base toner? It’s irreplaceable in my routine.
I also love that it doesn’t sting my eyes, doesn’t cause any sensitivity, and is gentle enough to use on my body as well as my face. A toner I can use absolutely everywhere — at this price point — is genuinely rare.
On drier days or after heavy sun exposure, I swap in the Shirojyun Premium for an extra boost of nourishment. The two work beautifully together, and I’ve been thinking about using Premium full-time in winter while keeping the original for warmer months.
I’m also planning to try the Gokujyun Light — it’s also glycerin-free, so I’m curious to see how it compares.
Hada Labo vs Hada Labo Tokyo — Are They the Same?
This is one of the most common points of confusion — and it’s worth clearing up before you buy.
The short answer: they are completely different products.
Hada Labo Tokyo (hadalabotokyo.com) is a separate brand manufactured by Mentholatum (also a Rohto subsidiary) specifically for the American market. Despite sharing a similar name, the product lineup, formulations, and pricing are all different from the original Japanese Hada Labo.
| Hada Labo (Japan) | Hada Labo Tokyo (US) | |
|---|---|---|
| Manufacturer | Rohto Pharmaceutical | Mentholatum (Rohto subsidiary) |
| Target market | Japan / Asia / Global | United States |
| Product range | 6 series + 40+ products | 6 products only |
| Preservatives | Paraben-based | Paraben-free |
| Packaging | Pump / bottle with refill pouches | Tube-style |
| Price | ~¥500–¥2,000 | $17–$28 (~¥2,500–¥4,000) |
| Where to buy | Japanese drugstores, iHerb, YesStyle, Amazon Japan | hadalabotokyo.com, US drugstores |
If you want the original Japanese formula — the one you see everywhere in Japanese drugstores and beauty communities online — look for it on iHerb, YesStyle, or Amazon Japan. Even if the label is in English, as long as it says “Made in Japan,” you’re getting the real thing.
Where to Buy Hada Labo Outside Japan
If you’re based in Japan, you’ll find Hada Labo at virtually every supermarket, drugstore, and variety store — it’s truly everywhere.
If you’re shopping from outside Japan, here are your best options:
- iHerb — Great selection, reliable shipping, competitive prices. Look for “Made in Japan” on the label.
- YesStyle — Wide range including newer and premium versions.
- Amazon Japan — Direct from Japan, often the most complete selection.
All three of these will get you the genuine Japanese formula — not the Hada Labo Tokyo version.
Final Thoughts
Rohto Pharmaceutical has created something genuinely special with the Hada Labo lineup — a range of products that are clean, research-backed, effective, and accessible to almost everyone. I’m not being dramatic when I say this brand has been one of the most consistent and reliable parts of my skincare routine for years.
Whether you’re new to Japanese skincare or already a convert, there’s a Hada Labo for your skin. Start with the one that matches your concern, use it consistently, and let the hyaluronic acid do its thing.
Have a favourite Hada Labo product, or still deciding which one to try? Drop a comment — I’d love to help you find your match! 🌸
Next up: my recommendations for where to buy Japanese skincare online — a complete shopping guide for international buyers. Stay tuned!

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